Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07JRL
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| Former ID |
DIB006933
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| Drug Name |
Epithalon
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| Synonyms |
Epitalon; BDM-E; Epitalon (Russian Academy of Medical Sciences); Retinal disease therapeutic, Biodiem; L-Alanyl-L-glutamyl-L-aspartyl-glycine
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| Drug Type |
Small molecular drug
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| Indication | Ocular inflammation [ICD-11: 9C61.24; ICD-10: H40.4; ICD-9: 370.33] | Phase 1/2 | [1] | |
| Company |
BioDiem Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C14H22N4O9
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| Canonical SMILES |
CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N
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| InChI |
1S/C14H22N4O9/c1-6(15)12(25)17-7(2-3-9(19)20)14(27)18-8(4-10(21)22)13(26)16-5-11(23)24/h6-8H,2-5,15H2,1H3,(H,16,26)(H,17,25)(H,18,27)(H,19,20)(H,21,22)(H,23,24)/t6-,7-,8-/m0/s1
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| InChIKey |
HGHOBRRUMWJWCU-FXQIFTODSA-N
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| CAS Number |
CAS 64082-79-7
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Telomerase reverse transcriptase (TERT) | Target Info | Modulator | [2] |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
| Regulation of Telomerase | ||||
| IL2 signaling events mediated by PI3K | ||||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021226) | |||
| REF 2 | Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med. 2003 Jun;135(6):590-2. | |||
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