Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07ONY
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| Former ID |
DNC012548
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| Drug Name |
5-(3-Chloro-benzyl)-1H-pyrazole-3-carboxylic acid
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| Synonyms |
CHEMBL394441; 595610-55-2; 1H-Pyrazole-3-carboxylic acid, 5-[(3-chlorophenyl)methyl]-; SCHEMBL569462; 5-(3-Chloro-benzyl)-1H-pyrazole-3-carboxylic acid; CTK1D9284; DTXSID30472377; BDBM50216550; AKOS030620128; 5-meta-chlorobenzyl-3-carboxyl-pyrazole; 5-(3-Chlorobenzyl)-1H-pyrazole-3-carboxylic acid; 3-(3-chlorobenzyl)-1H-pyrazole-5-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H9ClN2O2
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| Canonical SMILES |
C1=CC(=CC(=C1)Cl)CC2=CC(=NN2)C(=O)O
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| InChI |
1S/C11H9ClN2O2/c12-8-3-1-2-7(4-8)5-9-6-10(11(15)16)14-13-9/h1-4,6H,5H2,(H,13,14)(H,15,16)
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| InChIKey |
UYMDSFKYOCEPFN-UHFFFAOYSA-N
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| CAS Number |
CAS 595610-55-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acid receptor (HCAR2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pyrazole derivatives as partial agonists for the nicotinic acid receptor. J Med Chem. 2003 Aug 28;46(18):3945-51. | |||
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