Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07RRV
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| Drug Name |
Tetra-hydro-triazolopyrimidine derivative 2
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| Synonyms |
PMID29171765-Compound-Figure4
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| Company |
CHIESI FARMACEUTICI S.p.A. BLENCH, Toby Jonathan EDWARDS, Christine HEALD, Robert Andrew KULAGOWSKI, Janusz Jozef SUTTON, Jonathan Mark CAPALDI, CarmelidBoehringer Ingelheim International GmbBayer Intellectual Property GmbH
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neutrophil elastase (NE) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Neutrophil elastase (NE) | Target's Patent Info | [1] | |
| KEGG Pathway | Transcriptional misregulation in cancer | |||
| Systemic lupus erythematosus | ||||
| Pathway Interaction Database | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling | |||
| C-MYB transcription factor network | ||||
| Reactome | Collagen degradation | |||
| Degradation of the extracellular matrix | ||||
| Activation of Matrix Metalloproteinases | ||||
| WikiPathways | Hair Follicle Development: Cytodifferentiation (Part 3 of 3) | |||
| Human Complement System | ||||
| Degradation of collagen | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Serine protease inhibitors to treat inflammation: a patent review (2011-2016).Expert Opin Ther Pat. 2018 Feb;28(2):93-110. | |||
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