Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07VLC
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| Drug Name |
Fluorophenyl-substituted heterocyclic amide analog 1
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| Synonyms |
PMID27724045-Compound-9
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| Drug Type |
Small molecular drug
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| Company |
Roche
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| Structure |
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Download2D MOL |
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| Formula |
C21H16FN3O2
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| Canonical SMILES |
C1C(N(C=CC1=O)C(=O)NC2=CC=CC3=C2C=CC=N3)C4=CC=C(C=C4)F
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| InChI |
1S/C21H16FN3O2/c22-15-8-6-14(7-9-15)20-13-16(26)10-12-25(20)21(27)24-19-5-1-4-18-17(19)3-2-11-23-18/h1-12,20H,13H2,(H,24,27)/t20-/m0/s1
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| InChIKey |
ZREAHQPXWUVTDX-FQEVSTJZSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Antagonist | [1] |
| Target's Patent Info | P2X purinoceptor 7 (P2RX7) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Reactome | The NLRP3 inflammasome | |||
| WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | P2X7 receptor antagonists: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Mar;27(3):257-267. | |||
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