Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08KYQ
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| Drug Name |
Sulopenem
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| Synonyms |
CP-70,429; PF-03709270; PF-3,709,270
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| Drug Type |
Small molecular drug
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| Indication | Urinary tract infection [ICD-11: GC08; ICD-10: N39, N39.0] | Phase 3 | [1] | |
| Therapeutic Class |
Antiinfective Agents
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| Structure |
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Download2D MOL |
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| Formula |
C12H15NO5S3
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| Canonical SMILES |
CC(C1C2N(C1=O)C(=C(S2)SC3CCS(=O)C3)C(=O)O)O
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| InChI |
1S/C12H15NO5S3/c1-5(14)7-9(15)13-8(11(16)17)12(20-10(7)13)19-6-2-3-21(18)4-6/h5-7,10,14H,2-4H2,1H3,(H,16,17)/t5-,6+,7+,10-,21-/m1/s1
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| InChIKey |
FLSUCZWOEMTFAQ-PRBGKLEPSA-N
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| CAS Number |
CAS 120788-07-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Penicillin binding protein (Bact PBP) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03357614) Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults. U.S. National Institutes of Health. | |||
| REF 2 | In vitro antibacterial activity of a new parenteral penem, sulopenem. Jpn J Antibiot. 1996 Apr;49(4):324-37. | |||
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