Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08OKB
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| Drug Name |
Bicyclic heteroaryl amide derivative 2
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| Synonyms |
PMID27724045-Compound-24
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| Drug Type |
Small molecular drug
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| Company |
H. LUNDBECK A/S
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H31FN4O2
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| Canonical SMILES |
CC1(C2CCC(C1C2)CNC(=O)C3=CC=CC4=NC(=CN43)C(=O)N5CCC(CC5)F)C
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| InChI |
1S/C24H31FN4O2/c1-24(2)16-7-6-15(18(24)12-16)13-26-22(30)20-4-3-5-21-27-19(14-29(20)21)23(31)28-10-8-17(25)9-11-28/h3-5,14-18H,6-13H2,1-2H3,(H,26,30)/t15-,16-,18-/m0/s1
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| InChIKey |
AOWWKPWFEIOIDV-BQFCYCMXSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Antagonist | [1] |
| Target's Patent Info | P2X purinoceptor 7 (P2RX7) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Reactome | The NLRP3 inflammasome | |||
| WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | P2X7 receptor antagonists: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Mar;27(3):257-267. | |||
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