Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08QCJ
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| Former ID |
DAP000664
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| Drug Name |
Thiabendazole
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| Synonyms |
Biogard; Bioguard; Bovizole; Cropasal; Drawipas; Eprofil; Equizole; Hymush; Lombristop; Mertec; Mertect; Mintesol; Mintezol; Mintezole; Minzolum; Mycozol; Nemacin; Nemapan; Omnizole; Ormogal; Pitrizet; Polival; RPH; Sistesan; Storite; Tbdz; Tebuzate; Tecto; Testo; Thiaben; Thiabendazol; Thiabendazolum; Thiabendole; Thiabenzazole; Thiabenzole; Thibendole; Thibenzol; Thibenzole; Thiprazole; Tiabenda; Tiabendazol; Tiabendazole; Tiabendazolum; Tobaz; Tresaderm; Triasox; Tubazole; Captan T; Equivet TZ; Equizole A; Helmindrax octelmin; Hokustar HP; Mertect lsp; RTU Flowable Fungicide; Tecto B; Tecto rph; Thibenzole att; Top Form Wormer; Chemviron TK 100; G 491; MK 360; Mertect 160; Mertect 340f; Metasol TK 100; Metasol tk 10; PS1057_SUPELCO; Sanaizol 100; Syntol M100; TBZ 6; TBZ 60W; Tecto 10P; Tecto 40F; Tecto 60; Thibenzole 200; Tibimix 20; APL-luster; Arbotect (TN); MK-360; Metasol TK-100; Mintezol (TN); TBZ-6; Thiabendazole (USP); Thiabendazole [BSI:ISO]; Thiabendazole [USAN:BAN]; Tiabendazolum [INN-Latin]; Tresaderm (TN); E-Z-Ex; Mintezol, Equizole, Thiabendazole; Tiabendazol [INN-Spanish, French]; Tiabendazole (JAN/INN); 2-(1,3-Thiazol-4-yl)-1H-benzimidazole; 2-(1,3-Thiazol-4-yl)benzimidazole; 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole; 2-(4'-Thiazolyl)benzimidazole; 2-(4-Thiazolyl)-1H-benzimidazole; 2-(4-Thiazolyl)benzimidazole; 2-(Thiazol-4-yl)benzimidazole; 2-Thiazol-4-yl-1H-benzoimidazole; 2-Thiazole-4-ylbenzimidazole; 2-[4-Thiazoly]benzimidazole; 4-(1H-benzimidazol-2-yl)-1,3-thiazole; 4-(2-Benzimidazolyl)thiazole
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| Drug Type |
Small molecular drug
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| Indication | Dutch elm disease [ICD-11: 8D64] | Approved | [1], [2], [3] | |
| Helminth infection [ICD-11: 1F90.0] | Approved | [1], [2], [3] | ||
| Therapeutic Class |
Antinematodal Agents
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| Structure |
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Download2D MOL |
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| Formula |
C10H7N3S
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| Canonical SMILES |
C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
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| InChI |
1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
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| InChIKey |
WJCNZQLZVWNLKY-UHFFFAOYSA-N
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| CAS Number |
CAS 148-79-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9341, 397296, 481912, 603021, 855607, 906414, 3319048, 4262837, 5643850, 7847438, 7868816, 7890801, 7980772, 8149550, 8153342, 10321759, 10508572, 10589481, 11112304, 11335247, 11360486, 11362813, 11365375, 11367937, 11372373, 11373926, 11376099, 11408671, 11446358, 11453179, 11461458, 11466552, 11467672, 11485217, 11486164, 11489147, 11491222, 11492169, 11493853, 11534461, 14717006, 15195537, 17389714, 24869246, 24899102, 24900297, 24900571, 26611942, 26679510, 26697097
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| ChEBI ID |
CHEBI:45979
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| ADReCS Drug ID | BADD_D02196 | |||
| SuperDrug ATC ID |
D01AC06; P02CA02
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| SuperDrug CAS ID |
cas=000148798
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Fumarate reductase flavoprotein (Bact frdA) | Target Info | Inhibitor | [4] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7304). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 016096. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Fumarate reductase is essential for Helicobacter pylori colonization of the mouse stomach. Microb Pathog. 2000 Nov;29(5):279-87. | |||
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