Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08UQS
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| Former ID |
DCL000879
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| Drug Name |
MEM-1003
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| Synonyms |
SCHEMBL1191960; SCHEMBL16332975
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| Drug Type |
Small molecular drug
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| Indication | Bipolar disorder [ICD-11: 6A60; ICD-10: F31] | Phase 2a | [1] | |
| Dementia [ICD-11: 6D80-6D86] | Phase 2 | [2] | ||
| Company |
Bayer
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| Structure |
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Download2D MOL |
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| Formula |
C22H25ClN2O5
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| Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC(=C2Cl)C#N)C(=O)OCCOC
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| InChI |
1S/C22H25ClN2O5/c1-12(2)30-22(27)18-14(4)25-13(3)17(21(26)29-10-9-28-5)19(18)16-8-6-7-15(11-24)20(16)23/h6-8,12,19,25H,9-10H2,1-5H3
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| InChIKey |
GTIKSQYSAKETQA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated L-type calcium channel (L-CaC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for bipolar disorder. Expert Opin Emerg Drugs. 2006 Nov;11(4):621-34. | |||
| REF 2 | Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73. | |||
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