Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08VUJ
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| Former ID |
DIB006670
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| Drug Name |
ABT-202
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| Synonyms |
A-429202
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD-11: MG30-MG3Z] | Discontinued in Phase 1 | [1] | |
| Company |
NeuroSearch A/S
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| Structure |
 |
Download2D MOL |
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| Formula |
C9H13N3
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| Canonical SMILES |
C1CN(CC1N)C2=CN=CC=C2
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| InChI |
1S/C9H13N3/c10-8-3-5-12(7-8)9-2-1-4-11-6-9/h1-2,4,6,8H,3,5,7,10H2
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| InChIKey |
LVGMMVAWLISWJD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acetylcholine receptor (nAChR) | Target Info | Modulator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015975) | |||
| REF 2 | Modulators of nicotinic acetylcholine receptors as analgesics. Curr Opin Investig Drugs. 2004 Jan;5(1):76-81. | |||
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