Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09BZJ
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| Former ID |
DIB000471
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| Drug Name |
MEHD-7945A
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| Synonyms |
RG-7597; EGFR/HER3 dual monoclonal antibody, Genentech
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| Indication | Colorectal cancer [ICD-11: 2B91.Z] | Phase 2 | [1], [2] | |
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 2 | [2] | ||
| Company |
Genentech Inc
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01577173) A Study of MEHD7945A Versus Cetuximab in Patients With Recurrent/Metastatic Squamous Cell Carcinoma of The Head And Neck | |||
| REF 2 | ClinicalTrials.gov (NCT01652482) A Study of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI in Second Line in Patients With KRAS Wild-Type Metastatic Colorectal Cancer. U.S. National Institutes of Health. | |||
| REF 3 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | |||
| REF 4 | Bispecific antibodies rise again. Nat Rev Drug Discov. 2014 Nov;13(11):799-801. | |||
| REF 5 | Company report (Biooncology) | |||
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