| Target and Pathway |
Top |
| Target(s) |
Janus kinase 3 (JAK-3) |
Target Info
|
Inhibitor |
[1] |
| LCK tyrosine protein kinase (LCK) |
Target Info
|
Inhibitor |
[1] |
| Stress-activated protein kinase 2a (p38 alpha) |
Target Info
|
Inhibitor |
[1] |
| Vascular endothelial growth factor receptor 2 (KDR) |
Target Info
|
Inhibitor |
[1] |
|
KEGG Pathway
|
MAPK signaling pathway
|
|
Rap1 signaling pathway
|
|
FoxO signaling pathway
|
|
Sphingolipid signaling pathway
|
|
Adrenergic signaling in cardiomyocytes
|
|
VEGF signaling pathway
|
|
Osteoclast differentiation
|
|
Signaling pathways regulating pluripotency of stem cells
|
|
Platelet activation
|
|
Toll-like receptor signaling pathway
|
|
NOD-like receptor signaling pathway
|
|
RIG-I-like receptor signaling pathway
|
|
T cell receptor signaling pathway
|
|
Fc epsilon RI signaling pathway
|
|
TNF signaling pathway
|
|
Leukocyte transendothelial migration
|
|
Neurotrophin signaling pathway
|
|
Retrograde endocannabinoid signaling
|
|
Dopaminergic synapse
|
|
Inflammatory mediator regulation of TRP channels
|
|
GnRH signaling pathway
|
|
Progesterone-mediated oocyte maturation
|
|
Prolactin signaling pathway
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Epithelial cell signaling in Helicobacter pylori infection
|
|
Shigellosis
|
|
Salmonella infection
|
|
Pertussis
|
|
Leishmaniasis
|
|
Chagas disease (American trypanosomiasis)
|
|
Toxoplasmosis
|
|
Tuberculosis
|
|
Hepatitis C
|
|
Influenza A
|
|
Epstein-Barr virus infection
|
|
Proteoglycans in cancer
|
|
NF-kappa B signaling pathway
|
|
Natural killer cell mediated cytotoxicity
|
|
HTLV-I infection
|
|
Primary immunodeficiency
|
|
Ras signaling pathway
|
|
Cytokine-cytokine receptor interaction
|
|
Endocytosis
|
|
PI3K-Akt signaling pathway
|
|
Focal adhesion
|
|
Chemokine signaling pathway
|
|
Jak-STAT signaling pathway
|
|
Measles
|
|
Viral carcinogenesis
|
|
NetPath Pathway
|
IL5 Signaling Pathway
|
|
FSH Signaling Pathway
|
|
TCR Signaling Pathway
|
|
IL2 Signaling Pathway
|
|
Panther Pathway
|
Alzheimer disease-amyloid secretase pathway
|
|
Angiogenesis
|
|
B cell activation
|
|
EGF receptor signaling pathway
|
|
FGF signaling pathway
|
|
Interferon-gamma signaling pathway
|
|
Oxidative stress response
|
|
Parkinson disease
|
|
TGF-beta signaling pathway
|
|
Toll receptor signaling pathway
|
|
VEGF signaling pathway
|
|
Ras Pathway
|
|
p53 pathway feedback loops 2
|
|
p38 MAPK pathway
|
|
CCKR signaling map ST
|
|
T cell activation
|
|
Interleukin signaling pathway
|
|
JAK/STAT signaling pathway
|
|
PDGF signaling pathway
|
|
Pathwhiz Pathway
|
Fc Epsilon Receptor I Signaling in Mast Cells
|
|
Pathway Interaction Database
|
Endothelins
|
|
BCR signaling pathway
|
|
p73 transcription factor network
|
|
p38 MAPK signaling pathway
|
|
Atypical NF-kappaB pathway
|
|
IL4-mediated signaling events
|
|
CD40/CD40L signaling
|
|
IL12-mediated signaling events
|
|
Regulation of p38-alpha and p38-beta
|
|
CDC42 signaling events
|
|
Angiopoietin receptor Tie2-mediated signaling
|
|
FAS (CD95) signaling pathway
|
|
Thromboxane A2 receptor signaling
|
|
Role of Calcineurin-dependent NFAT signaling in lymphocytes
|
|
Glucocorticoid receptor regulatory network
|
|
IL2-mediated signaling events
|
|
Rapid glucocorticoid signaling
|
|
Regulation of Androgen receptor activity
|
|
ATF-2 transcription factor network
|
|
IL6-mediated signaling events
|
|
p38 signaling mediated by MAPKAP kinases
|
|
Retinoic acid receptors-mediated signaling
|
|
CXCR3-mediated signaling events
|
|
Signaling mediated by p38-alpha and p38-beta
|
|
EPO signaling pathway
|
|
Signaling events mediated by VEGFR1 and VEGFR2
|
|
p53 pathway
|
|
S1P2 pathway
|
|
Trk receptor signaling mediated by the MAPK pathway
|
|
VEGFR3 signaling in lymphatic endothelium
|
|
FGF signaling pathway
|
|
RAC1 signaling pathway
|
|
Regulation of retinoblastoma protein
|
|
Glypican 1 network
|
|
TCR signaling in naï
|
|
|
|
Signaling events mediated by PTP1B
|
|
TCR signaling in naï
|
|
|
|
SHP2 signaling
|
|
CXCR4-mediated signaling events
|
|
Class I PI3K signaling events
|
|
IL2 signaling events mediated by PI3K
|
|
amb2 Integrin signaling
|
|
EPHA forward signaling
|
|
PDGFR-beta signaling pathway
|
|
IL2 signaling events mediated by STAT5
|
|
Ephrin B reverse signaling
|
|
Alpha-synuclein signaling
|
|
HIF-2-alpha transcription factor network
|
|
Beta3 integrin cell surface interactions
|
|
Signaling events mediated by TCPTP
|
|
S1P1 pathway
|
|
VEGF and VEGFR signaling network
|
|
Integrins in angiogenesis
|
|
Notch-mediated HES/HEY network
|
|
Reactome
|
NOD1/2 Signaling Pathway
|
|
p38MAPK events
|
|
ERK/MAPK targets
|
|
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
|
|
Oxidative Stress Induced Senescence
|
|
CDO in myogenesis
|
|
DSCAM interactions
|
|
ADP signalling through P2Y purinoceptor 1
|
|
Platelet sensitization by LDL
|
|
VEGFA-VEGFR2 Pathway
|
|
activated TAK1 mediates p38 MAPK activation
|
|
Activation of the AP-1 family of transcription factors
|
|
KSRP (KHSRP) binds and destabilizes mRNA
|
|
GPVI-mediated activation cascade
|
|
PIP3 activates AKT signaling
|
|
Regulation of KIT signaling
|
|
Phosphorylation of CD3 and TCR zeta chains
|
|
Translocation of ZAP-70 to Immunological synapse
|
|
Generation of second messenger molecules
|
|
PECAM1 interactions
|
|
Constitutive Signaling by Aberrant PI3K in Cancer
|
|
DAP12 signaling
|
|
CD28 co-stimulation
|
|
CD28 dependent PI3K/Akt signaling
|
|
CD28 dependent Vav1 pathway
|
|
CTLA4 inhibitory signaling
|
|
PD-1 signaling
|
|
Interleukin-2 signaling
|
|
Neurophilin interactions with VEGF and VEGFR
|
|
VEGF binds to VEGFR leading to receptor dimerization
|
|
Integrin cell surface interactions
|
|
EPHA-mediated growth cone collapse
|
|
VEGFR2 mediated cell proliferation
|
|
Interleukin-7 signaling
|
|
G beta:gamma signalling through PI3Kgamma
|
|
RAF/MAP kinase cascade
|
|
Interleukin receptor SHC signaling
|
|
WikiPathways
|
Toll-like receptor signaling pathway
|
|
Monoamine Transport
|
|
Serotonin HTR1 Group and FOS Pathway
|
|
TCR Signaling Pathway
|
|
Senescence and Autophagy in Cancer
|
|
Interferon type I signaling pathways
|
|
Insulin Signaling
|
|
EGF/EGFR Signaling Pathway
|
|
MAPK Cascade
|
|
Oxidative Stress
|
|
p38 MAPK Signaling Pathway
|
|
IL-4 Signaling Pathway
|
|
MAPK Signaling Pathway
|
|
TGF beta Signaling Pathway
|
|
Kit receptor signaling pathway
|
|
Cardiac Hypertrophic Response
|
|
MAP kinase activation in TLR cascade
|
|
Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
|
|
Nanoparticle-mediated activation of receptor signaling
|
|
Structural Pathway of Interleukin 1 (IL-1)
|
|
JAK/STAT
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Alpha 6 Beta 4 signaling pathway
|
|
Cardiac Progenitor Differentiation
|
|
BDNF signaling pathway
|
|
Integrated Pancreatic Cancer Pathway
|
|
Oncostatin M Signaling Pathway
|
|
Parkinsons Disease Pathway
|
|
Corticotropin-releasing hormone
|
|
AGE/RAGE pathway
|
|
B Cell Receptor Signaling Pathway
|
|
Prostate Cancer
|
|
TSLP Signaling Pathway
|
|
TWEAK Signaling Pathway
|
|
FSH signaling pathway
|
|
Leptin signaling pathway
|
|
RANKL/RANK Signaling Pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in leukocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
IL-1 signaling pathway
|
|
Signal amplification
|
|
Platelet homeostasis
|
|
NGF signalling via TRKA from the plasma membrane
|
|
Myogenesis
|
|
DSCAM interactions
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
|
Angiogenesis
|
|
Physiological and Pathological Hypertrophy of the Heart
|
|
Regulation of toll-like receptor signaling pathway
|
|
Notch Signaling Pathway
|
|
IL-2 Signaling Pathway
|
|
Inflammatory Response Pathway
|
|
Signaling by SCF-KIT
|
|
DAP12 interactions
|
|
Host Interactions of HIV factors
|
|
PIP3 activates AKT signaling
|
|
T-Cell Receptor and Co-stimulatory Signaling
|
|
TCR signaling
|
|
Costimulation by the CD28 family
|
|
Focal Adhesion
|
|
Nifedipine Activity
|
|
Signaling by VEGF
|
|
Interleukin-2 signaling
|
|
Interleukin-7 signaling
|
|
IL-9 Signaling Pathway
|
|
IL-7 Signaling Pathway
|
|
Interleukin-3, 5 and GM-CSF signaling
|
