Drug Information
Drug General Information | Top | |||
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Drug ID |
D09VFQ
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Former ID |
DNC010231
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Drug Name |
NSC-745794
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Synonyms |
NSC-745794; CHEMBL604073
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C23H17N3O2
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Canonical SMILES |
CN(C)C1=CC=C(C=C1)C2=NC3=C(N2)C=CC4=C3C(=O)C5=CC=CC=C5C4=O
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InChI |
1S/C23H17N3O2/c1-26(2)14-9-7-13(8-10-14)23-24-18-12-11-17-19(20(18)25-23)22(28)16-6-4-3-5-15(16)21(17)27/h3-12H,1-2H3,(H,24,25)
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InChIKey |
ILPRDEDKIAQCMC-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
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REF 1 | Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28. |
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