Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09YVN
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| Former ID |
DNC003183
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| Drug Name |
Dihydrofolic Acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H21N7O6
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| Canonical SMILES |
C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
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| InChI |
1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t12-/m0/s1
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| InChIKey |
OZRNSSUDZOLUSN-LBPRGKRZSA-N
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| CAS Number |
CAS 4033-27-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3705, 219467, 7887020, 8143289, 10230047, 15007999, 15201936, 26707966, 44429037, 47349646, 50100134, 53787799, 57336759, 75381546, 103232782, 103918104, 104423382, 126523774, 128884694, 135055769, 137156388, 137240138, 142230122, 162221354, 163134117, 164808930, 172097268, 223785832, 226399521, 241084564, 250135219, 252141364, 252319440
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| ChEBI ID |
CHEBI:15633
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Polypeptide deformylase (PDF) | Target Info | Inhibitor | [1] |
| Pathwhiz Pathway | Folate Metabolism | |||
| Pterine Biosynthesis | ||||
| Reactome | E2F mediated regulation of DNA replication | |||
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | ||||
| Metabolism of folate and pterines | ||||
| G1/S-Specific Transcription | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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