Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A8BK
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| Former ID |
DIB004572
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| Drug Name |
MEN-10979
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| Synonyms |
MEN 10979; AC1LA5PO
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus-1 infection [ICD-11: 1C62; ICD-10: B20-B24] | Terminated | [1] | |
| Company |
The Menarini Group
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| Structure |
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Download2D MOL |
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| Formula |
C16H14N4S2
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| Canonical SMILES |
CCN1C2=C(C(=S)N(C3=C1N=CC=C3)C)SC4=C2N=CC=C4
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| InChI |
1S/C16H14N4S2/c1-3-20-13-12-11(7-5-8-17-12)22-14(13)16(21)19(2)10-6-4-9-18-15(10)20/h4-9H,3H2,1-2H3
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| InChIKey |
YRSMQXBXGMENSN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008234) | |||
| REF 2 | New arylpyrido-diazepine and -thiodiazepine derivatives are potent and highly selective HIV-1 inhibitors targeted at the reverse transcriptase. Antiviral Res. 1996 May;30(2-3):109-24. | |||
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