Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A8EV
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| Drug Name |
Triazolo-pyridine derivative 6
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| Synonyms |
PMID27321640-Compound-53
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| Drug Type |
Small molecular drug
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| Company |
LUNDBECK & CO AS H [DK]
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H10ClFN4
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| Canonical SMILES |
CC1=NC2=C(C(=CC=C2)F)N3C1=NN=C3C4=CC=CC=C4Cl
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| InChI |
1S/C16H10ClFN4/c1-9-15-20-21-16(10-5-2-3-6-11(10)17)22(15)14-12(18)7-4-8-13(14)19-9/h2-8H,1H3
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| InChIKey |
ZXWSCYGUZHTXLO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 10A (PDE10) | Target Info | Inhibitor | [1] |
| Phosphodiesterase 2A (PDE2A) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Phosphodiesterase 10A (PDE10) | Target's Patent Info | [1] | |
| Phosphodiesterase 2A (PDE2A) | Target's Patent Info | [1] | ||
| KEGG Pathway | Purine metabolism | |||
| Morphine addiction | ||||
| cGMP-PKG signaling pathway | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2016 Aug;26(8):933-46. | |||
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