Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A8HX
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| Former ID |
DNC012800
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| Drug Name |
6-m-Tolyl-pteridine-2,4,7-triamine
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| Synonyms |
6-(3-methylphenyl)pteridine-2,4,7-triamine; 2853-70-5; UNII-Y75RNL3DWL; Y75RNL3DWL; CHEMBL48189; NSC19443; NSC 19443; 6-m-Tolyl-pteridine-2,4,7-triamine; NSC 639358; AC1Q4WBT; AC1L5FLS; CTK4G1672; DTXSID00182754; ZINC1566881; 6-meta-tolylpteridine-2,7-triamine; NSC639358; NSC-19443; BDBM50127144; 6-(m-tolyl)pteridine-2,4,7-triamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H13N7
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| Canonical SMILES |
CC1=CC(=CC=C1)C2=NC3=C(N=C(N=C3N=C2N)N)N
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| InChI |
1S/C13H13N7/c1-6-3-2-4-7(5-6)8-10(14)18-12-9(17-8)11(15)19-13(16)20-12/h2-5H,1H3,(H6,14,15,16,18,19,20)
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| InChIKey |
YCKFHKBIDNIARX-UHFFFAOYSA-N
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| CAS Number |
CAS 2853-70-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Polypeptide deformylase (PDF) | Target Info | Inhibitor | [1] |
| Pathwhiz Pathway | Folate Metabolism | |||
| Pterine Biosynthesis | ||||
| Reactome | E2F mediated regulation of DNA replication | |||
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | ||||
| Metabolism of folate and pterines | ||||
| G1/S-Specific Transcription | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three ... J Med Chem. 2003 Apr 24;46(9):1726-36. | |||
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