Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0AL3G
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| Former ID |
DNC013097
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| Drug Name |
1-(3,4-dichlorobenzyl)-1H-imidazole
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| Synonyms |
1-(3,4-dichlorobenzyl)-1H-imidazole; CHEMBL379436; 56643-72-2; 1-(3,4-Dichloro-benzyl)-1H-imidazole; 1-(3,4-Dichlorobenzyl)imidazole; BAS 11721008; AC1MGEX9; CTK1F4149; DTXSID40388096; MolPort-000-511-619; ZINC4385934; BDBM50188095; STK951804; AKOS000586982; [(3,4-dichlorophenyl)methyl]imidazole; MCULE-5938366655; 1-[(3,4-dichlorophenyl)methyl]imidazole; ST50162194; 1H-Imidazole, 1-[(3,4-dichlorophenyl)methyl]-; SR-01000301759
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H8Cl2N2
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| Canonical SMILES |
C1=CC(=C(C=C1CN2C=CN=C2)Cl)Cl
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| InChI |
1S/C10H8Cl2N2/c11-9-2-1-8(5-10(9)12)6-14-4-3-13-7-14/h1-5,7H,6H2
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| InChIKey |
AYZFQKPOALRPNQ-UHFFFAOYSA-N
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| CAS Number |
CAS 56643-72-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Steroidogenesis | ||||
| Reactome | Androgen biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Steroid Biosynthesis | ||||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| Prostate Cancer | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hy... Bioorg Med Chem Lett. 2006 Aug 1;16(15):4011-5. | |||
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