Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0D1KZ
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| Former ID |
DNC006458
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| Drug Name |
1-methyl-1H-indole-3-carbaldehyde
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| Synonyms |
1-Methyl-1H-indole-3-carbaldehyde; 19012-03-4; 1-Methylindole-3-carboxaldehyde; 1-methylindole-3-carbaldehyde; 3-Formyl-1-methylindole; 1-Methyl-indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 1-methyl-; 1-Methyl-3-formylindole; N-Methyl-3-formylindole; Indole-3-carboxaldehyde, 1-methyl-; 3-Formyl-1-methyl-1H-indole; CHEMBL210779; N-Methyl-3-indolecarboxaldehyde; KXYBYRKRRGSZCX-UHFFFAOYSA-N; MFCD00014570; 1-Methylindole-3-carboxaldehyde, 97%; NSC83042; EINECS 242-750-3; PubChem7503; AI3-51477; AC1L3EMK; AC1Q6QCU; AC1Q3YTB
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H9NO
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| Canonical SMILES |
CN1C=C(C2=CC=CC=C21)C=O
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| InChI |
1S/C10H9NO/c1-11-6-8(7-12)9-4-2-3-5-10(9)11/h2-7H,1H3
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| InChIKey |
KXYBYRKRRGSZCX-UHFFFAOYSA-N
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| CAS Number |
CAS 19012-03-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Guanosine nucleotides de novo biosynthesis | ||||
| Superpathway of purine nucleotide salvage | ||||
| Purine nucleotides de novo biosynthesis | ||||
| Guanosine ribonucleotides de novo biosynthesis | ||||
| KEGG Pathway | Purine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Panther Pathway | De novo purine biosynthesis | |||
| Reactome | Purine ribonucleoside monophosphate biosynthesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. | |||
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