Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D6SZ
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| Former ID |
DIB004613
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| Drug Name |
TROXACITABINE
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| Synonyms |
Troxatyl; BCH-4556; SPD-758; Troxacitabine < Prop INN; Beta-L-OddC; (-)-beta-L-Dioxolanecytidine
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 2 | [1] | |
| Company |
Shire Pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C8H11N3O4
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| Canonical SMILES |
C1C(OC(O1)CO)N2C=CC(=NC2=O)N
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| InChI |
1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1
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| InChIKey |
RXRGZNYSEHTMHC-BQBZGAKWSA-N
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| CAS Number |
CAS 145918-75-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:134886
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human Deoxyribonucleic acid (hDNA) | Target Info | Binder | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00129948) Study for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML). U.S. National Institutes of Health. | |||
| REF 2 | Troxacitabine. Bull Cancer. 2004 Mar;91(3):213-8. | |||
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