Drug Information
Drug General Information | Top | |||
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Drug ID |
D0DT4R
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Former ID |
DNC003118
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Drug Name |
Brodimoprim-4,6-Dicarboxylate
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Synonyms |
brodimoprim-4,6-dicarboxylate; (2S)-2-[3-[2-bromo-5-[(2,4-diaminopyrimidin-1-ium-5-yl)methyl]-3-methoxyphenoxy]propyl]pentanedioate; (2S)-2-(3-{2-bromo-5-[(2,4-diaminopyrimidin-1-ium-5-yl)methyl]-3-methoxyphenoxy}propyl)pentanedioate; AC1NRA8B
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C20H24BrN4O6-
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Canonical SMILES |
COC1=C(C(=CC(=C1)CC2=C[NH+]=C(N=C2N)N)OCCCC(CCC(=O)[O-])C(=O)[O-])Br
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InChI |
1S/C20H25BrN4O6/c1-30-14-8-11(7-13-10-24-20(23)25-18(13)22)9-15(17(14)21)31-6-2-3-12(19(28)29)4-5-16(26)27/h8-10,12H,2-7H2,1H3,(H,26,27)(H,28,29)(H4,22,23,24,25)/p-1/t12-/m0/s1
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InChIKey |
SZAVCZNFKJSWRN-LBPRGKRZSA-M
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Polypeptide deformylase (PDF) | Target Info | Inhibitor | [1] |
Pathwhiz Pathway | Folate Metabolism | |||
Pterine Biosynthesis | ||||
Reactome | E2F mediated regulation of DNA replication | |||
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | ||||
Metabolism of folate and pterines | ||||
G1/S-Specific Transcription |
References | Top | |||
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REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
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