Drug Information
Drug General Information | Top | |||
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Drug ID |
D0DX3V
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Former ID |
DNC004199
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Drug Name |
7-Ethoxy-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
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Synonyms |
CHEMBL98812; SCHEMBL10760128; 2H-Imidazo[4,5-b]quinolin-2-one, 7-ethoxy-1,3-dihydro-; BDBM50229572
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H11N3O2
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Canonical SMILES |
CCOC1=CC2=CC3=C(NC(=O)N3)N=C2C=C1
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InChI |
1S/C12H11N3O2/c1-2-17-8-3-4-9-7(5-8)6-10-11(13-9)15-12(16)14-10/h3-6H,2H2,1H3,(H2,13,14,15,16)
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InChIKey |
SBMFEGWRZYIWGG-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Purine metabolism | |||
cGMP-PKG signaling pathway | ||||
cAMP signaling pathway | ||||
Morphine addiction | ||||
Reactome | cGMP effects | |||
G alpha (s) signalling events | ||||
WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
miR-targeted genes in lymphocytes - TarBase |
References | Top | |||
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REF 1 | 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation. J Med Chem. 1991 Sep;34(9):2906-16. |
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