Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0E2FZ
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| Former ID |
DIB005599
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| Drug Name |
ICA-69673
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| Synonyms |
ICA-069673; Ion channel modulators (epilepsy), ICAgen; Ion channel modulators, ICAgen/ArQule
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| Indication | Pain [ICD-11: MG30-MG3Z] | Preclinical | [1] | |
| Company |
Icagen Inc
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| Structure |
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Download2D MOL |
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| Formula |
C11H6ClF2N3O
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| Canonical SMILES |
C1=CC(=C(C=C1C(=O)NC2=CN=C(N=C2)Cl)F)F
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| InChI |
1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
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| InChIKey |
IIBSHMFXVWTQSJ-UHFFFAOYSA-N
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| CAS Number |
CAS 582323-16-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv7.2 (KCNQ2) | Target Info | Modulator | [2] |
| Voltage-gated potassium channel Kv7.3 (KCNQ3) | Target Info | Modulator | [2] | |
| KEGG Pathway | Cholinergic synapse | |||
| Panther Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||
| Reactome | Voltage gated Potassium channels | |||
| Interaction between L1 and Ankyrins | ||||
| WikiPathways | Potassium Channels | |||
| L1CAM interactions | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011004) | |||
| REF 2 | Voltage-gated Potassium Channels as Therapeutic Drug Targets | |||
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