Drug Information
Drug General Information | Top | |||
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Drug ID |
D0E3NZ
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Former ID |
DIB001377
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Drug Name |
L-696229
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Synonyms |
3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridine-2(1H)-one
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Drug Type |
Small molecular drug
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Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Discontinued in Phase 2 | [1] | |
Structure |
Download2D MOL |
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Formula |
C17H18N2O2
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Canonical SMILES |
CCC1=C(NC(=O)C(=C1)CCC2=NC3=CC=CC=C3O2)C
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InChI |
1S/C17H18N2O2/c1-3-12-10-13(17(20)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)21-16/h4-7,10H,3,8-9H2,1-2H3,(H,18,20)
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InChIKey |
MHUVLRNBDLFMHQ-UHFFFAOYSA-N
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CAS Number |
CAS 135525-71-2
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [2], [3] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001460) | |||
REF 2 | L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro.. Antimicrob Agents Chemother. 1992 May; 36(5): 1019-1023. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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