Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F2IC
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| Former ID |
DIB015245
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| Drug Name |
NTx-488
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| Synonyms |
Prolactin-containing multiple sclerosis therapy, Stem Cell Therapeutics
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| Indication | Multiple sclerosis [ICD-11: 8A40; ICD-9: 340] | Discontinued in Phase 2 | [1] | |
| Company |
Stem Cell Therapeutics Corp
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prolactin (PRL) | Target Info | Modulator | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Neuroactive ligand-receptor interaction | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Prolactin signaling pathway | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | ErbB4 signaling events | |||
| Signaling events mediated by PTP1B | ||||
| Glucocorticoid receptor regulatory network | ||||
| Validated nuclear estrogen receptor alpha network | ||||
| Reactome | Prolactin receptor signaling | |||
| Amyloid formation | ||||
| Growth hormone receptor signaling | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| EV release from cardiac cells and their functional effects | ||||
| Prolactin receptor signaling | ||||
| Growth hormone receptor signaling | ||||
| JAK/STAT | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028330) | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028330) | |||
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