Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F4NA
|
|||
| Former ID |
DNC008116
|
|||
| Drug Name |
N-(4-iodophenyl)-4-(trifluoromethyl)benzamide
|
|||
| Synonyms |
N-(4-iodophenyl)-4-(trifluoromethyl)benzamide; CHEMBL401308; AC1LKJKC; SCHEMBL7557294; MolPort-002-827-048; ZINC682493; BDBM50231097; AKOS008920216; MCULE-1341396811
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H9F3INO
|
|||
| Canonical SMILES |
C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)I)C(F)(F)F
|
|||
| InChI |
1S/C14H9F3INO/c15-14(16,17)10-3-1-9(2-4-10)13(20)19-12-7-5-11(18)6-8-12/h1-8H,(H,19,20)
|
|||
| InChIKey |
VTVLWVLMDYRPGZ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of benzamide derivatives as TRPV1 antagonists. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1072-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.