Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0FC5T
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| Former ID |
DIB015824
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| Drug Name |
DIAVERIDINE
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| Synonyms |
Diaveridine < Rec INN; EGIS-5645; 2,4-Diamino-5-(3',4'-dimethoxybenzyl)pyrimidine; 5-[(3,4-Dimethoxyphenyl)methyl]-2,4-pyrimidinediamine
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Terminated | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H16N4O2
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| Canonical SMILES |
COC1=C(C=C(C=C1)CC2=CN=C(N=C2N)N)OC
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| InChI |
1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
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| InChIKey |
LDBTVAXGKYIFHO-UHFFFAOYSA-N
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| CAS Number |
CAS 5355-16-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:123115
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Dihydrofolate reductase (Bact DHFR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002763) | |||
| REF 2 | Acute and sub-chronic toxicity study of diaveridine in Wistar rats.Regul Toxicol Pharmacol.2015 Oct;73(1):232-40. | |||
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