Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G0UZ
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| Former ID |
DIB001587
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| Drug Name |
SBP-002
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| Synonyms |
Coramsine; Solasonine + solamargine; Solasodine glycosides (cancer, injectable formulation), Solbec; Solasodine glycosides (psoriasis, cream formulation), Solbec; Solasonine + solamargine (cancer), Solbec; Solasonine + solamargine (psoriasis), Solbec; SBP-002 (intravenous, cancer), Solbec; SBP-002 (psoriasis, cream formulation), Solbec
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| Indication | Melanoma [ICD-11: 2C30; ICD-9: 172] | Terminated | [1] | |
| Company |
Curacel International Pty Ltd; Freedom Eye Ltd
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 6 receptor (IL6R) | Target Info | Modulator | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| HIF-1 signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Non-alcoholic fatty liver disease (NAFLD) | ||||
| Reactome | MAPK3 (ERK1) activation | |||
| MAPK1 (ERK2) activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Senescence and Autophagy in Cancer | ||||
| IL-6 signaling pathway | ||||
| Differentiation Pathway | ||||
| Interleukin-6 signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022850) | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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