Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0G3ZH
|
|||
Former ID |
DNC009661
|
|||
Drug Name |
N-(quinolin-8-yl)-6-(sulfamoylamino)hexanamide
|
|||
Synonyms |
CHEMBL507114; N-(quinolin-8-yl)-6-(sulfamoylamino)hexanamide; SCHEMBL5330834
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C15H20N4O3S
|
|||
Canonical SMILES |
C1=CC2=C(C(=C1)NC(=O)CCCCCNS(=O)(=O)N)N=CC=C2
|
|||
InChI |
1S/C15H20N4O3S/c16-23(21,22)18-11-3-1-2-9-14(20)19-13-8-4-6-12-7-5-10-17-15(12)13/h4-8,10,18H,1-3,9,11H2,(H,19,20)(H2,16,21,22)
|
|||
InChIKey |
IQEBALPYRTUOEG-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Histone deacetylase 6 (HDAC6) | Target Info | Inhibitor | [1] |
KEGG Pathway | Alcoholism | |||
Viral carcinogenesis | ||||
Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
Signaling events mediated by HDAC Class I | ||||
Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
Assembly of the primary cilium | ||||
WikiPathways | Ectoderm Differentiation | |||
Neural Crest Differentiation | ||||
Cell Cycle |
References | Top | |||
---|---|---|---|---|
REF 1 | Sulfamides as novel histone deacetylase inhibitors. Bioorg Med Chem Lett. 2009 Jan 15;19(2):336-40. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.