Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GC7S
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| Former ID |
DNC006768
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| Drug Name |
1-phenyl-3-(3-(pyridin-2-yl)isoquinolin-1-yl)urea
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| Synonyms |
CHEMBL70553; 1-phenyl-3-(3-(pyridin-2-yl)isoquinolin-1-yl)urea; BDBM50088465; 1-Phenyl-3-[3-(2-pyridyl)-1-isoquinolyl]urea
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C21H16N4O
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| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)NC2=NC(=CC3=CC=CC=C32)C4=CC=CC=N4
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| InChI |
1S/C21H16N4O/c26-21(23-16-9-2-1-3-10-16)25-20-17-11-5-4-8-15(17)14-19(24-20)18-12-6-7-13-22-18/h1-14H,(H2,23,24,25,26)
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| InChIKey |
IJXVHHOSRPNGFG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Inhibitor | [1] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. | |||
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