Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GX8F
|
|||
| Former ID |
DNC005127
|
|||
| Drug Name |
BN-82002
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | M-phase inducer phosphatase 3 (MPIP3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cell cycle | |||
| Oocyte meiosis | ||||
| Progesterone-mediated oocyte maturation | ||||
| MicroRNAs in cancer | ||||
| Panther Pathway | p53 pathway | |||
| Pathway Interaction Database | ATR signaling pathway | |||
| ATM pathway | ||||
| PLK1 signaling events | ||||
| PLK3 signaling events | ||||
| Reactome | Polo-like kinase mediated events | |||
| Cyclin B2 mediated events | ||||
| Activation of ATR in response to replication stress | ||||
| RHO GTPases activate PKNs | ||||
| Cyclin A/B1 associated events during G2/M transition | ||||
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | ||||
| WikiPathways | Monoamine Transport | |||
| DNA Damage Response | ||||
| ATM Signaling Pathway | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Mitotic G2-G2/M phases | ||||
| Cell Cycle | ||||
| Cell Cycle Checkpoints | ||||
| miRNA Regulation of DNA Damage Response | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of small molecule CDC25 phosphatases inhibitors. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12. | |||
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