Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0HR8H
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| Former ID |
DNC002828
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| Drug Name |
(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
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| Synonyms |
(5s)-5-iododihydro-2,4(1h,3h)-pyrimidinedione; IDH; AC1NRBRW; SCHEMBL4316335; DB02303; (5S)-5-iodo-1,3-diazinane-2,4-dione
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C4H5IN2O2
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| Canonical SMILES |
C1C(C(=O)NC(=O)N1)I
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| InChI |
1S/C4H5IN2O2/c5-2-1-6-4(9)7-3(2)8/h2H,1H2,(H2,6,7,8,9)/t2-/m0/s1
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| InChIKey |
YGKCTZPSAOUUMT-REOHCLBHSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dihydrothymine dehydrogenase (DPYD) | Target Info | Inhibitor | [1] |
| BioCyc | Pyrimidine ribonucleosides degradation | |||
| Thymine degradation | ||||
| Uracil degradation | ||||
| KEGG Pathway | Pyrimidine metabolism | |||
| beta-Alanine metabolism | ||||
| Pantothenate and CoA biosynthesis | ||||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Panther Pathway | Pyrimidine Metabolism | |||
| Pathwhiz Pathway | Beta-Alanine Metabolism | |||
| Pyrimidine Metabolism | ||||
| WikiPathways | Metabolism of nucleotides | |||
| Fluoropyrimidine Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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