Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0HR8H
|
|||
Former ID |
DNC002828
|
|||
Drug Name |
(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
|
|||
Synonyms |
(5s)-5-iododihydro-2,4(1h,3h)-pyrimidinedione; IDH; AC1NRBRW; SCHEMBL4316335; DB02303; (5S)-5-iodo-1,3-diazinane-2,4-dione
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C4H5IN2O2
|
|||
Canonical SMILES |
C1C(C(=O)NC(=O)N1)I
|
|||
InChI |
1S/C4H5IN2O2/c5-2-1-6-4(9)7-3(2)8/h2H,1H2,(H2,6,7,8,9)/t2-/m0/s1
|
|||
InChIKey |
YGKCTZPSAOUUMT-REOHCLBHSA-N
|
|||
PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Dihydrothymine dehydrogenase (DPYD) | Target Info | Inhibitor | [1] |
BioCyc | Pyrimidine ribonucleosides degradation | |||
Thymine degradation | ||||
Uracil degradation | ||||
KEGG Pathway | Pyrimidine metabolism | |||
beta-Alanine metabolism | ||||
Pantothenate and CoA biosynthesis | ||||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Panther Pathway | Pyrimidine Metabolism | |||
Pathwhiz Pathway | Beta-Alanine Metabolism | |||
Pyrimidine Metabolism | ||||
WikiPathways | Metabolism of nucleotides | |||
Fluoropyrimidine Activity |
References | Top | |||
---|---|---|---|---|
REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.