Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J7NR
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| Former ID |
DNC004192
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| Drug Name |
5-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
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| Synonyms |
CHEMBL319551; 2H-Imidazo[4,5-b]quinolin-2-one, 1,3-dihydro-5-methyl-; BDBM50229556
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H9N3O
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| Canonical SMILES |
CC1=C2C(=CC=C1)C=C3C(=N2)NC(=O)N3
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| InChI |
1S/C11H9N3O/c1-6-3-2-4-7-5-8-10(13-9(6)7)14-11(15)12-8/h2-5H,1H3,(H2,12,13,14,15)
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| InChIKey |
YZNZOJPHYDBVIZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation. J Med Chem. 1991 Sep;34(9):2906-16. | |||
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