Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J7TM
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| Former ID |
DAP001314
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| Drug Name |
Benzylpenicilloyl Polylysine
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| Synonyms |
Benzylpenicilloyl; Benzylpenicilloyl G; Benzylpenicilloyl G polylysine; Benzylpenicilloyl-polylysine; Penicilloyl-polylysine; 2-(2-((5-Carboxypentyl)amino)-2-oxo-1-((phenylacetyl)amino)ethyl)-5,5-dimethyl-4-thiazolidinecarboxylic acid; 2-[2-[(6-hydroxy-6-oxohexyl)amino]-2-oxo-1-[(2-phenylacetyl)amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Approved | [1], [2] | |
| Therapeutic Class |
Analgesics
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| Structure |
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Download2D MOL
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| Formula |
C28H46N6O8S
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| Canonical SMILES |
CC1(C(NC(S1)C(C(=O)NCCCCC(C(=O)O)N)NC(=O)CC2=CC=CC=C2)C(=O)O)C.C(CCN)CC(C(=O)O)N
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| InChI |
1S/C22H32N4O6S.C6H14N2O2/c1-22(2)17(21(31)32)26-19(33-22)16(25-15(27)12-13-8-4-3-5-9-13)18(28)24-11-7-6-10-14(23)20(29)30;7-4-2-1-3-5(8)6(9)10/h3-5,8-9,14,16-17,19,26H,6-7,10-12,23H2,1-2H3,(H,24,28)(H,25,27)(H,29,30)(H,31,32);5H,1-4,7-8H2,(H,9,10)/t14-,16?,17+,19-;5-/m11/s1
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| InChIKey |
IMPVZRLKKKXMKQ-SGDOCVTFSA-N
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| CAS Number |
CAS 31855-75-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:59297
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| ADReCS Drug ID | BADD_D00250 ; BADD_D00251 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Immunoglobulin epsilon Fc receptor gamma (FCERG) | Target Info | Binder | [3] |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Fc epsilon RI signaling pathway | ||||
| Asthma | ||||
| Pathwhiz Pathway | Fc Epsilon Receptor I Signaling in Mast Cells | |||
| Reactome | Fc epsilon receptor (FCERI) signaling | |||
| Role of LAT2/NTAL/LAB on calcium mobilization | ||||
| FCERI mediated MAPK activation | ||||
| FCERI mediated Ca+2 mobilization | ||||
| FCERI mediated NF-kB activation | ||||
| WikiPathways | IL1 and megakaryotyces in obesity | |||
| Fc epsilon receptor (FCERI) signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Benzylpenicilloyl Polylysine, 2008. eduDrugs. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | Penicillin allergy: anti-penicillin IgE antibodies and immediate hypersensitivity skin reactions employing major and minor determinants of penicillin. Arch Dis Child. 1980 Nov;55(11):857-60. | |||
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