Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0J8KR
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| Former ID |
DNC002734
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| Drug Name |
ISOPENTENYL PYROPHOSPHATE
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| Synonyms |
isopentenyl pyrophosphate; isopentenyl diphosphate; 3-Methyl-3-butenyl pyrophosphate; IPPP; Mono(3-methyl-3-butenyl) diphosphate; delta3-Isopentenyl diphosphate; isopentenyl-pp; Diphosphoric acid mono(3-methyl-3-butenyl) ester; delta-3-Isopentenyl pyrophosphat; Isopentenyl-diphosphate; CHEBI:16584; delta3-methyl-3-butenyl diphosphate; 3-methylbut-3-enyl phosphono hydrogen phosphate; 358-71-4; delta-3-Isopentenyl pyrophosphate; 3-methylbut-3-en-1-yl trihydrogen diphosphate; 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C5H12O7P2
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| Canonical SMILES |
CC(=C)CCOP(=O)(O)OP(=O)(O)O
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| InChI |
1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h1,3-4H2,2H3,(H,9,10)(H2,6,7,8)
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| InChIKey |
NUHSROFQTUXZQQ-UHFFFAOYSA-N
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| CAS Number |
CAS 358-71-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3429, 4921752, 6436370, 7888448, 8143496, 8151020, 15465272, 24423989, 24439540, 24701609, 46508890, 50139704, 53788060, 56374398, 56436260, 56458864, 56458870, 57320806, 57646499, 79702911, 87226119, 87457602, 87457607, 87457611, 87457617, 87457618, 92728834, 93578169, 99455520, 103131117, 103388476, 104297029, 117628464, 125299586, 126407016, 126496995, 126523982, 127340954, 127340955, 127340956, 127340957, 128755821, 135073461, 135651495, 137009008, 139524402, 144080109, 144220562, 152255915, 160657435
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| ChEBI ID |
CHEBI:16584
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Undecaprenyl pyrophosphate synthetase (Bact ispU) | Target Info | Inhibitor | [2] |
| Geranyltranstransferase (FDPS) | Target Info | Inhibitor | [2] | |
| BioCyc | Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | |||
| Superpathway of cholesterol biosynthesis | ||||
| Trans, trans-farnesyl diphosphate biosynthesis | ||||
| Geranylgeranyldiphosphate biosynthesis | ||||
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Cholesterol biosynthesis | |||
| Pathwhiz Pathway | Steroid Biosynthesis | |||
| Reactome | Cholesterol biosynthesis | |||
| Activation of gene expression by SREBF (SREBP) | ||||
| WikiPathways | Activation of Gene Expression by SREBP (SREBF) | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3048). | |||
| REF 2 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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