Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0J9OS
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| Former ID |
DNC006457
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| Drug Name |
3-(furan-3-yl)-1-methyl-1H-indole
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| Synonyms |
CHEMBL207375; 3-(furan-3-yl)-1-methyl-1H-indole; 1H-Indole, 3-(3-furanyl)-1-methyl-; BDBM50182882
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H11NO
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| Canonical SMILES |
CN1C=C(C2=CC=CC=C21)C3=COC=C3
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| InChI |
1S/C13H11NO/c1-14-8-12(10-6-7-15-9-10)11-4-2-3-5-13(11)14/h2-9H,1H3
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| InChIKey |
UFMJKAKKDCGNEF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Guanosine nucleotides de novo biosynthesis | ||||
| Superpathway of purine nucleotide salvage | ||||
| Purine nucleotides de novo biosynthesis | ||||
| Guanosine ribonucleotides de novo biosynthesis | ||||
| KEGG Pathway | Purine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Panther Pathway | De novo purine biosynthesis | |||
| Reactome | Purine ribonucleoside monophosphate biosynthesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. | |||
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