Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K1CL
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| Former ID |
DIB014771
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| Drug Name |
SDZ-224-015
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| Synonyms |
VE-13045
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Terminated | [1] | |
| Company |
Sandoz Research Institute
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| Structure |
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Download2D MOL |
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| Formula |
C28H31Cl2N3O9
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| Canonical SMILES |
CC(C)C(C(=O)NC(C)C(=O)NC(C(=O)COC(=O)C1=C(C=CC=C1Cl)Cl)OCC=O)NC(=O)OCC2=CC=CC=C2
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| InChI |
1S/C28H31Cl2N3O9/c1-16(2)23(32-28(39)42-14-18-8-5-4-6-9-18)25(37)31-17(3)24(36)33-26(40-13-12-34)21(35)15-41-27(38)22-19(29)10-7-11-20(22)30/h4-12,16-17,23,26H,13-15H2,1-3H3,(H,31,37)(H,32,39)(H,33,36)/t17-,23-,26-/m0/s1
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| InChIKey |
ABGURXXQCVTOBD-RUJAXMSRSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006085) | |||
| REF 2 | Reduction of inflammation and pyrexia in the rat by oral administration of SDZ 224-015, an inhibitor of the interleukin-1 beta converting enzyme. Br J Pharmacol. 1995 Jun;115(4):601-6. | |||
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