Target and Pathway |
Top |
Target(s) |
Cyclin-dependent kinase 4 (CDK4) |
Target Info
|
Inhibitor |
[1] |
Cyclin-dependent kinase 6 (CDK6) |
Target Info
|
Inhibitor |
[1] |
Serine/threonine-protein kinase mTOR (mTOR) |
Target Info
|
Inhibitor |
[1] |
Smoothened homolog (SMO) |
Target Info
|
Inhibitor |
[1] |
Target's Patent Info |
Cyclin-dependent kinase 4 (CDK4) |
Target's Patent Info
|
[1] |
Cyclin-dependent kinase 6 (CDK6) |
Target's Patent Info
|
[1] |
Serine/threonine-protein kinase mTOR (mTOR) |
Target's Patent Info
|
[1] |
Smoothened homolog (SMO) |
Target's Patent Info
|
[1] |
KEGG Pathway
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Cell cycle
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p53 signaling pathway
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PI3K-Akt signaling pathway
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Tight junction
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T cell receptor signaling pathway
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Hepatitis B
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Measles
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HTLV-I infection
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Pathways in cancer
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Viral carcinogenesis
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Pancreatic cancer
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Glioma
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Melanoma
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Bladder cancer
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Chronic myeloid leukemia
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Small cell lung cancer
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Non-small cell lung cancer
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MicroRNAs in cancer
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Hedgehog signaling pathway
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Proteoglycans in cancer
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Basal cell carcinoma
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ErbB signaling pathway
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HIF-1 signaling pathway
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mTOR signaling pathway
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AMPK signaling pathway
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Insulin signaling pathway
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Thyroid hormone signaling pathway
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Adipocytokine signaling pathway
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Type II diabetes mellitus
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Prostate cancer
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Acute myeloid leukemia
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Central carbon metabolism in cancer
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Choline metabolism in cancer
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NetPath Pathway
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TCR Signaling Pathway
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EGFR1 Signaling Pathway
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RANKL Signaling Pathway
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TGF_beta_Receptor Signaling Pathway
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Panther Pathway
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Hedgehog signaling pathway
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Hypoxia response via HIF activation
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Interleukin signaling pathway
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Pathwhiz Pathway
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Leucine Stimulation on Insulin Signaling
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Pathway Interaction Database
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Regulation of nuclear SMAD2/3 signaling
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Validated targets of C-MYC transcriptional activation
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ATF-2 transcription factor network
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FOXM1 transcription factor network
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Regulation of retinoblastoma protein
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p73 transcription factor network
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Coregulation of Androgen receptor activity
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C-MYB transcription factor network
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IL2 signaling events mediated by STAT5
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Signaling events mediated by the Hedgehog family
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Hedgehog signaling events mediated by Gli proteins
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IL4-mediated signaling events
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Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
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IL12-mediated signaling events
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CDC42 signaling events
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LKB1 signaling events
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Regulation of Telomerase
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mTOR signaling pathway
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CXCR4-mediated signaling events
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EGFR-dependent Endothelin signaling events
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IL2 signaling events mediated by PI3K
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IFN-gamma pathway
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ErbB1 downstream signaling
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ErbB2/ErbB3 signaling events
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CXCR3-mediated signaling events
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Class I PI3K signaling events mediated by Akt
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Reactome
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Oxidative Stress Induced Senescence
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Senescence-Associated Secretory Phenotype (SASP)
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Oncogene Induced Senescence
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RMTs methylate histone arginines
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Transcriptional regulation of white adipocyte differentiation
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Ubiquitin-dependent degradation of Cyclin D1
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Cyclin D associated events in G1
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Meiotic recombination
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Class B/2 (Secretin family receptors)
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Hedgehog 'off' state
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Activation of SMO
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PIP3 activates AKT signaling
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Macroautophagy
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mTORC1-mediated signalling
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HSF1-dependent transactivation
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CD28 dependent PI3K/Akt signaling
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VEGFR2 mediated vascular permeability
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TP53 Regulates Metabolic Genes
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Constitutive Signaling by AKT1 E17K in Cancer
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WikiPathways
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DNA Damage Response
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G1 to S cell cycle control
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Ovarian Infertility Genes
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PPAR Alpha Pathway
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Bladder Cancer
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S Phase
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Transcriptional Regulation of White Adipocyte Differentiation
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Meiotic Recombination
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Retinoblastoma (RB) in Cancer
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Spinal Cord Injury
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Integrated Pancreatic Cancer Pathway
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Prostate Cancer
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Signaling Pathways in Glioblastoma
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TSH signaling pathway
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Integrated Breast Cancer Pathway
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Integrated Cancer pathway
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Mitotic G1-G1/S phases
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Cell Cycle
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miRNA Regulation of DNA Damage Response
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Wnt Signaling Pathway Netpath
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Metastatic brain tumor
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miR-targeted genes in muscle cell - TarBase
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miR-targeted genes in lymphocytes - TarBase
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miR-targeted genes in leukocytes - TarBase
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miR-targeted genes in epithelium - TarBase
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miRNAs involved in DNA damage response
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Hedgehog Signaling Pathway
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Hair Follicle Development: Organogenesis (Part 2 of 3)
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Hair Follicle Development: Induction (Part 1 of 3)
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GPCR ligand binding
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GPCRs, Other
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ErbB Signaling Pathway
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Senescence and Autophagy in Cancer
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Interferon type I signaling pathways
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Insulin Signaling
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EGF/EGFR Signaling Pathway
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Extracellular vesicle-mediated signaling in recipient cells
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Cardiac Hypertrophic Response
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Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
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PIP3 activates AKT signaling
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Polycystic Kidney Disease Pathway
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Alpha 6 Beta 4 signaling pathway
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BDNF signaling pathway
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Oncostatin M Signaling Pathway
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TSLP Signaling Pathway
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FSH signaling pathway
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Leptin signaling pathway
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RANKL/RANK Signaling Pathway
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SREBF and miR33 in cholesterol and lipid homeostasis
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SREBP signalling
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Signaling by Insulin receptor
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Costimulation by the CD28 family
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Type II diabetes mellitus
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MicroRNAs in cardiomyocyte hypertrophy
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TOR Signaling
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AMPK Signaling
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