Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KX3H
|
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| Former ID |
DNC001178
|
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| Drug Name |
Pyrrolopyrimidine
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C6H5N3
|
|||
| Canonical SMILES |
C1=CNC2=CN=CN=C21
|
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| InChI |
1S/C6H5N3/c1-2-8-6-3-7-4-9-5(1)6/h1-4,8H
|
|||
| InChIKey |
KDOPAZIWBAHVJB-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Multidrug resistance-associated protein 1 (ABCC1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | ABC transporters | |||
| Sphingolipid signaling pathway | ||||
| Vitamin digestion and absorption | ||||
| MicroRNAs in cancer | ||||
| NetPath Pathway | IL6 Signaling Pathway | |||
| Pathway Interaction Database | S1P1 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | Cobalamin (Cbl, vitamin B12) transport and metabolism | |||
| ABC-family proteins mediated transport | ||||
| WikiPathways | Arachidonic acid metabolism | |||
| Irinotecan Pathway | ||||
| Metabolism of water-soluble vitamins and cofactors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Topological model for the prediction of MRP1 inhibitory activity of pyrrolopyrimidines and templates derived from pyrrolopyrimidine. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4967-72. | |||
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