Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L5XY
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| Former ID |
DNC003213
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| Drug Name |
FR221647
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| Synonyms |
FR-221647; CHEMBL13696; 256461-28-6; 1H-Imidazole-4-carboxamide, 1-[1-(hydroxymethyl)-3-phenylpropyl]-; 1H-Imidazole-4-carboxamide, 1-(1-(hydroxymethyl)-3-phenylpropyl)-; FR221647; ZUYUIKKHHBEVHL-UHFFFAOYSA-N; AC1MHQ05; SCHEMBL7659103; CTK0J3882; BDBM22917; imidazole-4-carboxamide derivative, 1; AKOS030619368; 1-(1-hydroxy-4-phenyl-2-butyl)imidazole-4-carboxamide; 1-(1-hydroxy-4-phenylbutan-2-yl)imidazole-4-carboxamide; 1-[1-(hydroxymethyl)-3-phenyl-propyl]imidazole-4-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H17N3O2
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| Canonical SMILES |
C1=CC=C(C=C1)CCC(CO)N2C=C(N=C2)C(=O)N
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| InChI |
1S/C14H17N3O2/c15-14(19)13-8-17(10-16-13)12(9-18)7-6-11-4-2-1-3-5-11/h1-5,8,10,12,18H,6-7,9H2,(H2,15,19)/t12-/m1/s1
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| InChIKey |
ZUYUIKKHHBEVHL-GFCCVEGCSA-N
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| CAS Number |
CAS 256461-28-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine deaminase (ADA) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Purine deoxyribonucleosides degradation | ||||
| Purine ribonucleosides degradation to ribose-1-phosphate | ||||
| Adenosine nucleotides degradation | ||||
| Superpathway of purine nucleotide salvage | ||||
| Adenine and adenosine salvage III | ||||
| KEGG Pathway | Purine metabolism | |||
| Metabolic pathways | ||||
| Primary immunodeficiency | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Panther Pathway | Adenine and hypoxanthine salvage pathway | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Pathway Interaction Database | p73 transcription factor network | |||
| C-MYB transcription factor network | ||||
| Validated transcriptional targets of deltaNp63 isoforms | ||||
| Validated transcriptional targets of TAp63 isoforms | ||||
| Reactome | Purine salvage | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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