Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0LC2B
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| Former ID |
DIB016194
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| Drug Name |
NSP-805
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| Synonyms |
TZN-01; 5-Methyl-6-[4-(2-methyl-3-oxo-1-cyclopentenylamino)phenyl]-2,3,4,5-tetrahydropyridazin-3-one
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| Drug Type |
Small molecular drug
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| Indication | Heart failure [ICD-11: BD10-BD13; ICD-10: I50, I50.9; ICD-9: 428] | Discontinued in Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H19N3O2
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| Canonical SMILES |
CC1CC(=O)NN=C1C2=CC=C(C=C2)NC3=C(C(=O)CC3)C
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| InChI |
1S/C17H19N3O2/c1-10-9-16(22)19-20-17(10)12-3-5-13(6-4-12)18-14-7-8-15(21)11(14)2/h3-6,10,18H,7-9H2,1-2H3,(H,19,22)
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| InChIKey |
DSRIICXPBQXOKK-UHFFFAOYSA-N
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| CAS Number |
CAS 125068-54-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3 (PDE3) | Target Info | Modulator | [2], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002110) | |||
| REF 2 | [The effect of phosphodiesterase type 3 inhibitor on chorio-retinal blood flow in rabbits eyes].Nippon Ganka Gakkai Zasshi.2002 Oct;106(10):615-20. | |||
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