Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M7DC
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| Former ID |
DNC012512
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| Drug Name |
1H-Pyrazole-3-carboxylic acid
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| Synonyms |
1H-Pyrazole-3-carboxylic acid; 1621-91-6; Pyrazole-3-carboxylic acid; 1H-Pyrazole-5-carboxylic acid; 2H-PYRAZOLE-3-CARBOXYLIC ACID; 5-Pyrazolecarboxylic acid; 3-Pyrazolecarboxylic acid; 797027-83-9; 3-carboxy-1h-pyrazole; Pyrazolic acid; CHEMBL128679; KOPFEFZSAMLEHK-UHFFFAOYSA-N; pyrazolecarboxylic; 3-Carboxypyrazole; 2H-PYRAZOLE-3-CARBOXYLICACID; zlchem 656; pyrazolecarboxylic acid; pyrazole-5-carboxylic; PubChem12935; AC1Q5UBI; AC1LCCJ7; 3-pyrazole carboxylic acid; pyrazole 3-carboxylic acid; ACMC-209z0p; Pyrazole-5-carboxylic a
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C4H4N2O2
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| Canonical SMILES |
C1=C(NN=C1)C(=O)O
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| InChI |
1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)
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| InChIKey |
KOPFEFZSAMLEHK-UHFFFAOYSA-N
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| CAS Number |
CAS 1621-91-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acid receptor (HCAR2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pyrazole derivatives as partial agonists for the nicotinic acid receptor. J Med Chem. 2003 Aug 28;46(18):3945-51. | |||
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