Drug Information
Drug General Information | Top | |||
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Drug ID |
D0M7RM
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Former ID |
DNC011319
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Drug Name |
NSC-640558
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Synonyms |
NSC-640558; NSC640558; CHEMBL1288281; 1-(2-(3,5-Diphenyl-1H-pyrazol-1-yl)-4-methyl-1,3-thiazol-5-yl)-3-phenyl-2-propen-1-one; AC1NYM1Y; AC1Q5G5M; 1-[2-(3,5-diphenyl-1H-pyrazol-1-yl)-4-methyl-1,3-thiazol-5-yl]-3-phenylprop-2-en-1-one; ZINC16957596; BDBM50332209; (E)-1-[2-(3,5-diphenylpyrazol-1-yl)-4-methyl-thiazol-5-yl]-3-phenyl-prop-2-en-1-one
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C28H21N3OS
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Canonical SMILES |
CC1=C(SC(=N1)N2C(=CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)C(=O)C=CC5=CC=CC=C5
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InChI |
1S/C28H21N3OS/c1-20-27(26(32)18-17-21-11-5-2-6-12-21)33-28(29-20)31-25(23-15-9-4-10-16-23)19-24(30-31)22-13-7-3-8-14-22/h2-19H,1H3/b18-17+
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InChIKey |
DDJHJUVZEFZWQV-ISLYRVAYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Quinone reductase 2 (NQO2) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. |
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