Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0MC5H
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| Former ID |
DNC009752
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| Drug Name |
2-(4-Chlorobenzylidene)cyclopentanone
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| Synonyms |
CHEMBL562352; 2-(4-Chlorobenzylidene)cyclopentanone; E-2-(4-chlorobenzylidene)cyclopentanone; BDBM50293435; AKOS027461656; 134791-44-9; (E)-2-(4-Chlorobenzylidene)cyclopentanone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H11ClO
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| Canonical SMILES |
C1CC(=CC2=CC=C(C=C2)Cl)C(=O)C1
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| InChI |
1S/C12H11ClO/c13-11-6-4-9(5-7-11)8-10-2-1-3-12(10)14/h4-8H,1-3H2/b10-8+
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| InChIKey |
WUMOJUUCPXEEQL-CSKARUKUSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dihydrodiol dehydrogenase type I (AKR1C3) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Allopregnanolone biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Arachidonic acid metabolism | ||||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Reactome | Retinoid metabolism and transport | |||
| WikiPathways | Metapathway biotransformation | |||
| Benzo(a)pyrene metabolism | ||||
| Arachidonic acid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3. Eur J Med Chem. 2009 Jun;44(6):2563-71. | |||
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