Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OX9F
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| Drug Name |
BIIB074
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| Synonyms |
CNV1014082; BC600719; HY-12796; B5927; (5R)-5-(4-[2-
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| Indication | Bipolar disorder [ICD-11: 6A60; ICD-10: F31] | Phase 2 | [1] | |
| Lumbosacral radiculopathy [ICD-11: 8B93.Y] | Phase 2 | [2] | ||
| Trigeminal neuralgia [ICD-11: 8B82.0; ICD-10: G50.0] | Phase 2 | [2], [3] | ||
| Company |
Biogen
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| Structure |
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Download2D MOL |
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| Formula |
C18H19FN2O2
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| Canonical SMILES |
C1CC(NC1C2=CC=C(C=C2)OCC3=CC=CC=C3F)C(=O)N
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| InChI |
1S/C18H19FN2O2/c19-15-4-2-1-3-13(15)11-23-14-7-5-12(6-8-14)16-9-10-17(21-16)18(20)22/h1-8,16-17,21H,9-11H2,(H2,20,22)/t16-,17+/m1/s1
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| InChIKey |
JESCETIFNOFKEU-SJORKVTESA-N
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| CAS Number |
CAS 934240-30-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.7 (SCN9A) | Target Info | Inhibitor | [2], [3] |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027679) | |||
| REF 2 | Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357. | |||
| REF 3 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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