Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0P1QW
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| Former ID |
DCL000715
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| Drug Name |
Becampanel
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| Synonyms |
AMP397; AMP-397; AMP-397A; [(7-nitro-2,3-dioxo-1,4-dihydroquinoxalin-5-yl)methylamino]methylphosphonic acid
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| Drug Type |
Small molecular drug
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| Indication | Epilepsy [ICD-11: 8A60-8A68] | Discontinued in Phase 2 | [1] | |
| Company |
Novartis
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| Structure |
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Download2D MOL |
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| Formula |
C10H11N4O7P
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| Canonical SMILES |
C1=C(C=C2C(=C1CNCP(=O)(O)O)NC(=O)C(=O)N2)[N+](=O)[O-]
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| InChI |
1S/C10H11N4O7P/c15-9-10(16)13-8-5(3-11-4-22(19,20)21)1-6(14(17)18)2-7(8)12-9/h1-2,11H,3-4H2,(H,12,15)(H,13,16)(H2,19,20,21)
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| InChIKey |
ABFMMCZFKUIJGQ-UHFFFAOYSA-N
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| CAS Number |
CAS 188696-80-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Antagonist | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22. | |||
| REF 2 | Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17. | |||
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