Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q0EY
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| Former ID |
DNC012082
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| Drug Name |
(S)-2-Amino-4-methyl-pentane-1-thiol
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| Synonyms |
CHEMBL448735; 88264-65-7; Leucinthiol; 2-Amino-4-methyl-pentane-1-thiol; L-LEUCINETHIOL; (S)-2-Amino-4-methyl-pentane-1-thiol; AC1L3ELJ; 1-Pentanethiol, 2-amino-4-methyl-, (2S)-; SCHEMBL2002339; GXEDNWSUKCJLLB-LURJTMIESA-N; ZINC403014; BDBM50078133; AKOS006342069; (S)-2-Amino-4-methyl-1-pentanethiol; (S)-2-Amino-4-methylpentane-1-thiol; (2S)-2-amino-4-methylpentane-1-thiol; 1-Pentanethiol, 2-amino-4-methyl-, (S)-; L-Leucinethiol, oxidized dihydrochloride, leucine aminopeptidase inhibitor
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H15NS
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| Canonical SMILES |
CC(C)CC(CS)N
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| InChI |
1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m0/s1
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| InChIKey |
GXEDNWSUKCJLLB-LURJTMIESA-N
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| CAS Number |
CAS 88264-65-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aminopeptidase N (ANPEP) | Target Info | Inhibitor | [1] |
| BioCyc | Glutathione-mediated detoxification | |||
| KEGG Pathway | Glutathione metabolism | |||
| Metabolic pathways | ||||
| Renin-angiotensin system | ||||
| Hematopoietic cell lineage | ||||
| Pathwhiz Pathway | Glutathione Metabolism | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | Metabolism of Angiotensinogen to Angiotensins | |||
| Cardiac Progenitor Differentiation | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett. 1999 Jun 7;9(11):1511-6. | |||
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