Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q3QS
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| Former ID |
DIB013800
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| Drug Name |
4-aminosalicylate sodium
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| Synonyms |
AGI-022; Salicylate prodrug (oralcontrolled release, ulcerative colitis), AGI Therapeutics; 4-ASA-Na; 4-ASA-Na (oral, controlled release), AGI Therapeutics
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| Drug Type |
Small molecular drug
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| Indication | Inflammatory bowel disease [ICD-11: DD72; ICD-10: K50-K52] | Phase 1 | [1] | |
| Company |
Athpharma Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C7H6NNaO3
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| Canonical SMILES |
C1=CC(=C(C=C1N)O)C(=O)[O-].[Na+]
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| InChI |
1S/C7H7NO3.Na/c8-4-1-2-5(7(10)11)6(9)3-4;/h1-3,9H,8H2,(H,10,11);/q;+1/p-1
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| InChIKey |
FVVDKUPCWXUVNP-UHFFFAOYSA-M
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| CAS Number |
133-10-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022712) | |||
| REF 2 | 5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis. Anticancer Res. 2012 Apr;32(4):1193-202. | |||
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