Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Q9WN
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Former ID |
DIB004911
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Drug Name |
FC EPO
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Synonyms |
Long acting erythropoietin (anemia), Merck Serono
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Indication | Anemia [ICD-11: 3A00-3A9Z; ICD-9: 280-285] | Discontinued in Phase 1 | [1] | |
Company |
Merck Serono SA
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Target and Pathway | Top | |||
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Target(s) | Erythropoietin (EPO) | Target Info | Agonist | [2] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
HIF-1 signaling pathway | ||||
PI3K-Akt signaling pathway | ||||
Jak-STAT signaling pathway | ||||
Hematopoietic cell lineage | ||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
Signaling events mediated by Stem cell factor receptor (c-Kit) | ||||
EPO signaling pathway | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
WikiPathways | EPO Receptor Signaling | |||
Hematopoietic Stem Cell Differentiation | ||||
Differentiation Pathway | ||||
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027346) | |||
REF 2 | Detection of EPO-Fc fusion protein in human blood: screening and confirmation protocols for sports drug testing. Drug Test Anal. 2012 Nov;4(11):818-29. |
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