Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0R8LN
|
|||
Former ID |
DNC009920
|
|||
Drug Name |
N-{4-[2-(3-Methoxyphenyl)ethyl]phenyl}phthalimide
|
|||
Synonyms |
CHEMBL572484; N-{4-[2-(3-Methoxyphenyl)ethyl]phenyl}phthalimide
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C23H19NO3
|
|||
Canonical SMILES |
COC1=CC=CC(=C1)CCC2=CC=C(C=C2)N3C(=O)C4=CC=CC=C4C3=O
|
|||
InChI |
1S/C23H19NO3/c1-27-19-6-4-5-17(15-19)10-9-16-11-13-18(14-12-16)24-22(25)20-7-2-3-8-21(20)23(24)26/h2-8,11-15H,9-10H2,1H3
|
|||
InChIKey |
CNZNMDJWLSHLJZ-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Oxysterols receptor LXR-alpha (NR1H3) | Target Info | Inhibitor | [1] |
Oxysterols receptor LXR-beta (NR1H2) | Target Info | Inhibitor | [1] | |
KEGG Pathway | PPAR signaling pathway | |||
Non-alcoholic fatty liver disease (NAFLD) | ||||
Hepatitis C | ||||
Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
Reactome | Nuclear Receptor transcription pathway | |||
WikiPathways | SREBP signalling | |||
Nuclear Receptors | ||||
Nuclear Receptors in Lipid Metabolism and Toxicity | ||||
Nuclear Receptors Meta-Pathway | ||||
PPAR Alpha Pathway | ||||
Liver X Receptor Pathway | ||||
Adipogenesis | ||||
SREBF and miR33 in cholesterol and lipid homeostasis |
References | Top | |||
---|---|---|---|---|
REF 1 | Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LX... Bioorg Med Chem. 2009 Jul 15;17(14):5001-14. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.