Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0RD5U
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| Former ID |
DNC012514
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| Drug Name |
PT-114
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| Synonyms |
181305-49-7; Thiourea, N-(5-chloro-2-pyridinyl)-N'-(2-(4-(dimethylamino)-2,6-difluorophenyl)ethyl)-; N-(2-(-2,6-Difluoro-4-(dimethylamino)phenethyl))-N'-(2-(5-chloropyridyl))thiourea; 1-(5-chloropyridin-2-yl)-3-[2-[4-(dimethylamino)-2,6-difluorophenyl]ethyl]thiourea; N-[2-(-2,6-Difluoro-4-(dimethylamino)phenethyl)]-N'-[2-(5-chloropyridyl)]thiourea; 1-(5-chloropyridin-2-yl)-3-{2-[4-(dimethylamino)-2,6-difluorophenyl]ethyl}thiourea; Thiourea, N-(5-chloro-2-pyridinyl)-N'-[2-[4-(dimethylamino)-2,6-difluorophenyl]ethy
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H17ClF2N4S
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| Canonical SMILES |
CN(C)C1=CC(=C(C(=C1)F)CCNC(=S)NC2=NC=C(C=C2)Cl)F
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| InChI |
1S/C16H17ClF2N4S/c1-23(2)11-7-13(18)12(14(19)8-11)5-6-20-16(24)22-15-4-3-10(17)9-21-15/h3-4,7-9H,5-6H2,1-2H3,(H2,20,21,22,24)
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| InChIKey |
CTKOUWBTBJGZKA-UHFFFAOYSA-N
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| CAS Number |
CAS 181305-49-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity r... J Med Chem. 1996 Oct 11;39(21):4261-74. | |||
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